HIV-1/copyright induced oxidative stress disrupts tight junction protein-1 in human pulmonary microvascular endothelial cells: role of Ras/ERK1/2 pathway.

Intravenous drug use (IVDU) is the major risk factor in the development of HIV-related pulmonary arterial hypertension (HRPAH); however, the pathogenesis of HRPAH in association with IVDU has yet to be characterized.Endothelial injury is considered to be an initiating factor for pulmonary vascular remodeling in animal models of PAH.Our previous stu

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Bad news about an old poison. A case of nicotine poisoning due to both ingestion and injection of the content of an electronic cigarette refill

There are increasing concerns about the escalating use of electronic cigarettes (e-cigarettes).In particular, smokers have been advised by important agencies such as the US Food and Drug Administration about the potential harm to the health of these products, being now considered Power Strips as drug delivery devices.The leading issues supporting t

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